Antibody-Binding Proteins and Conjugates
Cayman Chemical DIquafosolsodIum salt 50mg
A P2Y2 and P2Y4 receptor agonist (EC50s = 0.1 and 0.4 µM, respectively, in calcium mobilization assays); selective for P2Y2 and P2Y4 receptors over P2Y6 receptors (EC50 = 20 µM); induces the release of mucin-like glycoproteins from rabbit conjunctival goblet cells, as well as reduces desiccation-induced corneal damage in a rabbit model of dry eye disease at 0.1 and 1% w/v
Biotium Podocalyxin(3D3), CF488A conjugate, 0.1mg/mL
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is highly on kidney podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD282 / TLR2(TLR2/221), CF594 conjugate, 0.1mg/mL
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
Cayman Chemical UTPsodIum salt 500mg
A nucleotide and dual P2Y2 and P2Y4 receptor agonist (EC50s = 55 and 80 nM, respectively, for stimulation of phospholipase C in 1321N1 cells expressing human receptors); selective for P2Y2 and P2Y4 receptors over P2Y6 receptors (EC50 = >10,000 nM); stimulates proliferation of PANC-1 cells (EC50 = 13.1 μM), an effect that can be prevented by siRNA against the P2Y2 receptor; induces vasoconstriction in perfused isolated canine epicardial coronary artery; formed from UMP and can be converted to CTP; reacts with glucose-1-phosphate to form UDP-glucose
Revvity Health Sciences Inc AlphaLISA Anti-unmodified Histone H3 Lysine 4 (H3K4) Acceptor Beads, 250 ug
AlphaLISA Anti-unmodified Histone H3 Lysine 4 (H3K4) Acceptor Beads, 250 ug
Abcam PE/Cy7 Conjugation Kit - Lightning-Link, 600UG
The Abcam PE/Cy7 Conjugation Kit ( ab102903) offers several standout features: - Rapid Conjugation: Achieve PE/Cy7 labeling in under 4 hours with just 30 seconds of hands-on time. - High Efficiency: Ensures 100% antibody recovery, preserving the integrity and value of your antibodies. - Versatility: Suitable for conjugating antibodies, proteins, and peptides, and the labeled antibodies can be used immediately in applications such as Western Blotting (WB), ELISA, and Immunohistochemistry (IHC) without further purification. - Confidence- cited in over 15 publications.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical AzlocIlInsodIum salt 500mg
A semisynthetic with broad spectrum antibacterial properties; used as part of antibiotic cocktails known as PANTA (with polymyxin B, amphotericin B, nalidixic acid, and trimethoprim) and PANTAV (PANTA with vancomycin)
Cayman Chemical EtIdronatesodIum salt 500mg
A non-nitrogenous bisphosphonate that binds to hydroxyapatite and reduces osteoclast proliferation, thereby inhibiting abnormal bone resorption
Cayman Chemical MItIglInIdecalcIum salt 500mg
A SUR1/Kir6.2 inhibitor (IC50 = 4 nM); selective for SUR1/Kir6.2 over SUR2A/Kir6.2 and SUR2B/Kir6.2 channels (IC50s = 3 and 5 µM, respectively); induces insulin release in HIT-T15 insulinoma cells and isolated mouse pancreatic islets at 100 µM; increases postprandial plasma insulin levels and inhibits postprandial increases in plasma glucose levels in an STZ-induced rat model of diabetes
Cayman Chemical FAdodIum salt 50mg
A flavin dinucleotide; functions as a coenzyme that facilitates the transfer of electrons by flavoenzymes in oxidation-reduction reactions; reduces UV-B-induced death of human corneal epithelial cells in vitro
Abcam HRP Conjugation Kit - Lightning-Link, 1 x 5MG
Abcam's HRP Conjugation Kit (ab102890): Fast, Efficient, and Reliable - Rapid Conjugation: Achieve HRP conjugation in under 4 hours with just 30 seconds of hands-on time using the HRP Conjugation Kit ab102890. - High Efficiency: Ensures 100% antibody recovery, preserving the integrity and value of your antibodies. - Effortless Protocol: Add modifier to your antibody, incubate for 3 hours, then add quencher for 30 minutes, with no need for further purification. - Scalable: Compatible with most standard antibody formulations, effective for 10µg to 100mg of antibody. - Versatile Conjugation: Utilize Lightning-Link technology to conjugate with over 45 labels, including Alexa Fluor, DyLight, tandem dyes, enzymes, oligonucleotides, and gold nanoparticles. - Confidence: cited in over 60 publications
The product is subject to the following: Abcam Restricted Use Statement
Biotium Rhodamine Phalloidin, 300U
Phalloidin conjugates are actin filament stains for fixed and permeabilized cells. Red fluorescent rhodamine phalloidin has excitation/emission at 540/565 nm.
Columbia Biosciences Corp GT ANTI-GST DYLIGHT 488 100UG
Goat Anti-GST IgG, primary antibody, conjugated to DyLight 488, 100ug. Microscopy, Flow Cytometry and Cell Based Assays
Cayman Chemical ON-01910sodIum salt 25mg
A potent, non-ATP-competitive inhibitor of Plk1 (IC50 = 9 nM); induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM); active in vivo when administered intraperitoneally and synergizes with chemotherapeutic agents